Acrosome labelling in mammalian spermatozoa
نویسندگان
چکیده
منابع مشابه
Studies on acrosome labelling of mammalian spermatozoa by radioactive sugars.
The localization of glycoprotein synthesis and storage was studied during acrosome formation in guinea-pig using fine-structure autoradiography after (3H)-fucose incorporation. Three days after (3H)-fucose injection, labelling in spermatids was concentrated in the matrix of developing acrosomes, and it was evident that the fucosylation of acrosomal glycoproteins largely overshadowed the fucosyl...
متن کاملNAADP and the two-pore channel protein 1 participate in the acrosome reaction in mammalian spermatozoa
The functional relationship between the formation of hundreds of fusion pores during the acrosome reaction in spermatozoa and the mobilization of calcium from the acrosome has been determined only partially. Hence, the second messenger NAADP, promoting efflux of calcium from lysosome-like compartments and one of its potential molecular targets, the two-pore channel 1 (TPC1), were analyzed for i...
متن کاملRab3A triggers the acrosome reaction in permeabilized human spermatozoa.
The acrosome reaction is a regulated exocytotic process leading to a massive fusion between the outer acrosomal membrane and the cell membrane. In spite of the great amount of information available related to the acrosome reaction in several species, there is a remarkable paucity about the role of monomeric guanosine triphosphatases (GTPases) of the Rab family-well-established participants in e...
متن کاملProstasome-like vesicles stimulate acrosome reaction of pig spermatozoa
BACKGROUND The presence of small membranous particles characterizes the male genital fluids of different mammalian species. The influence of semen vesicles, denominated prostasomes, on sperm functional properties has been well documented in humans, but their biological activity is scarcely known in other species. The present work investigated prostasome-like vesicles in pig semen for their abil...
متن کاملTargeted and restricted complement activation on acrosome-reacted spermatozoa.
A specific hypoglycosylated isoform of the complement regulator membrane cofactor protein (MCP; CD46) is expressed on the inner acrosomal membrane (IAM) of spermatozoa. This membrane is exposed after the acrosome reaction, an exocytosis event that occurs upon contact with the zona pellucida. We initiated this investigation to assess MCP's regulatory function in situ on spermatozoa. Upon exposur...
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ژورنال
عنوان ژورنال: Annales de Biologie Animale Biochimie Biophysique
سال: 1979
ISSN: 0003-388X
DOI: 10.1051/rnd:19790513